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Article

Methylation and intratumoural heterogeneity of 14-3-3 sigma in oral cancer.

Oncology reports - 1 Oct 2007

Bhawal Ujjal Kumar, Tsukinoki Keiichi, Sasahira Tomonori, Sato Fuyuki, Mori Yusuke, Muto Noriko, Sugiyama Masaru, Kuniyasu Hiroki

Abstract excerpt

14-3-3 sigma has been a major G2/M checkpoint control gene and has demonstrated that its inactivation in various cancers occurs mostly by epigenetic hypermethylation, not by genetic change. This study investigated the methylation status and expression of the 14-3-3 sigma gene in 46 oral squamous...

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PMID: 17786341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17786341-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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