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Article

MMP-13 and p53 in the progression of malignant peripheral nerve sheath tumors.

Neoplasia (New York, N.Y.) - 1 Aug 2007

Holtkamp Nikola, Atallah Isis, Okuducu Ali-Fuat, Mucha Jana, Hartmann Christian, Mautner Victor-F, Friedrich Reinhard E, Mawrin Christian, von Deimling Andreas

Abstract excerpt

Malignant peripheral nerve sheath tumors (MPNST) are sarcomas with poor prognosis and limited treatment options. Factors contributing to tumor progression are largely unknown. We therefore examined MPNST from 22 neurofibromatosis type 1 (NF1) patients, 14 non-NF1 patients, and 14 neurofibroma patients for matrix metalloproteinase 13 (MMP-13) expression. Because wild-type and mutant p53 were shown to...

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Source

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Identifiers

PMID: 17786186
DOI: 10.1593/neo.07304
PMCID: PMC1950437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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