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Article

Malignant peripheral nerve sheath tumor cell invasion is facilitated by Src and aberrant CD44 expression.

Glia - 1 Jun 2003

Su Weiping, Sin Mihaela, Darrow Andrea, Sherman Larry S

Abstract excerpt

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive malignancies that arise within peripheral nerves. These tumors occur with increased incidence in patients with neurofibromatosis type 1 (NF1), exhibiting increased Ras activity due to loss of the NF1 gene product, neurofibromin, and abnormal expression of the epidermal growth factor receptor (EGFR). We previously found that MPNSTs express increased...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12730955
DOI: 10.1002/glia.10206

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Malignant peripheral nerve sheath tumor cell invasion is facilitated by Src and aberrant CD44 expression.PMID 12730955Read ↗

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