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Article

A Road Map Toward Defining the Role of Smad Signaling in Hematopoietic Stem Cells

16 Dec 2005

Abstract excerpt

The transforming growth factor-beta (TGF-beta) superfamily encompasses the ligands and receptors for TGF-beta, bone morphogenic proteins (BMPs), and Activins. Cellular response to ligand is context-dependent and may be controlled by specificity and/or redundancy of expression of these superfamily members. Several pathways within this family have been implicated in the proliferation, differentiation, and renewal...

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PMID: 16357343
DOI: 10.1634/stemcells.2005-0263

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