Article
Epidermal growth factor receptor mutation status and clinicopathological features of combined small cell carcinoma with adenocarcinoma of the lung.
Cancer science - 1 Nov 2007
Fukui Tomoya, Tsuta Koji, Furuta Koh, Watanabe Shun-Ichi, Asamura Hisao, Ohe Yuichiro, Maeshima Akiko Miyagi, Shibata Tatsuhiro, Masuda Noriyuki, Matsuno Yoshihiro
Abstract excerpt
In lung cancer, somatic mutations of epidermal growth factor receptor (EGFR) are concentrated in exons 18-21, especially in adenocarcinoma (Ad), but these mutations have rarely been reported in small cell lung carcinoma (SCLC). Combined SCLC is rare, and the EGFR mutation status and its relations...
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