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Article

Small-cell carcinoma with an epidermal growth factor receptor mutation in a never-smoker with gefitinib-responsive adenocarcinoma of the lung.

Clinical lung cancer - 1 Sept 2010

Alam Naheed, Gustafson Karen S, Ladanyi Marc, Zakowski Maureen F, Kapoor Atul, Truskinovsky Alexander M, Dudek Arkadiusz Z

Abstract excerpt

Activating mutations in the epidermal growth factor receptor (EGFR) gene are extremely rare in small-cell lung cancer (SCLC). Here, we present a case of an EGFR-mutant gefitinib-responsive non-small-cell lung cancer (NSCLC) of adenocarcinoma histology occurring in a never-smoker followed by subsequent diagnosis of metastatic SCLC carrying an EGFR mutation. Although gefitinib therapy of the primary NSCLC resulted...

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Source

Identifiers

PMID: 20837450
DOI: 10.3816/CLC.2010.n.046

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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