Article
Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk.
American journal of human genetics - 1 Jan 2003
Xu Jianfeng, Zheng S Lilly, Komiya Akira, Mychaleckyj Josyf C, Isaacs Sarah D, Chang Baoli, Turner Aubrey R, Ewing Charles M, Wiley Kathleen E, Hawkins Gregory A, Bleecker Eugene R, Walsh Patrick C, Meyers Deborah A, Isaacs William B
Abstract excerpt
Rare germline mutations of macrophage scavenger receptor 1 (MSR1) gene were reported to be associated with prostate cancer risk in families with hereditary prostate cancer (HPC) and in patients with non-HPC (Xu et al. 2002). To further evaluate the role of MSR1 in prostate cancer susceptibility, at Johns Hopkins Hospital, we studied five common variants of MSR1 in 301 patients with non-HPC who underwent prostate...
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