Article
Cytokine gene polymorphisms in preterm infants with necrotising enterocolitis: genetic association study.
Archives of disease in childhood. Fetal and neonatal edition - 1 Mar 2009
Henderson G, Craig S, Baier R J, Helps N, Brocklehurst P, McGuire W
Abstract excerpt
BACKGROUND: The inflammatory cytokine cascade is implicated in the pathogenesis of necrotising enterocolitis (NEC). Genetic association studies of cytokine polymorphisms may help to detect molecular mechanisms that are causally related to the disease process. AIM: To examine associations between the common genetic variants in candidate inflammatory cytokine genes and NEC in preterm infants. METHODS: Multi-centre...
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