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Article

The mutability of enzyme active-site shape determinants.

Protein science : a publication of the Protein Society - 1 Sept 2007

Miller Brian G

Abstract excerpt

Investigations of enzyme action typically focus on elucidating the catalytic roles of hydrogen bonding interactions between polar active-site residues and substrate molecules. Less clear is the importance of non-hydrogen bonding contacts to enzymatic rate accelerations. To investigate the importance of such interactions in a model system, six residues that participate in van der Waals contacts with substrate...

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Identifiers

PMID: 17766388
DOI: 10.1110/ps.073040307
PMCID: PMC2206970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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