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Article

Optimization of primer design for the detection of variable genomic lesions in cancer.

Bioinformatics (Oxford, England) - 1 Nov 2007

Bashir Ali, Liu Yu-Tsueng, Raphael Benjamin J, Carson Dennis, Bafna Vineet

Abstract excerpt

Primer approximation multiplex PCR (PAMP) is a new experimental protocol for efficiently assaying structural variation in genomes. PAMP is particularly suited to cancer genomes where the precise breakpoints of alterations such as deletions or translocations vary between patients. The design of PCR primer sets for PAMP is challenging because a large number of primer pairs are required to detect alterations in the...

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PMID: 17766270
DOI: 10.1093/bioinformatics/btm390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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