Article
Tumour necrosis factor a -308 promoter polymorphism in patients with rheumatoid arthritis.
Rheumatology international - 1 Dec 2007
Rezaieyazdi Zahra, Afshari Jalil Tavakol, Sandooghi Mahnaz, Mohajer Farnaz
Abstract excerpt
There are controversial reports that TNF-a promoter polymorphism may be an independent marker of susceptibility to rheumatoid arthritis (RA). We used Polymerase chain reaction amplification and Restriction fragment length polymorphism for analysis of the polymorphism at position -308 in promoter of TNF-alpha gene in 34 patients with RA and 30 healthy individuals. Distribution of TNF-genotypes in RA patients did...
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