Article
Inhibition of foot-and-mouth disease virus infections in cell cultures with antisense morpholino oligomers.
Journal of virology - 1 Nov 2007
Vagnozzi Ariel, Stein David A, Iversen Patrick L, Rieder Elizabeth
Abstract excerpt
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed ungulates that can lead to severe losses in the livestock production and export industries. Although vaccines have been extensively used to control FMD, there is no antiviral therapy available to treat ongoing infections with FMD virus (FMDV). Six peptide-conjugated morpholino oligomers (PPMOs) with sequences complementary to...
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