Article
Variation of the expression of Mycobacterium tuberculosis ppe44 gene among clinical isolates.
FEMS immunology and medical microbiology - 1 Nov 2007
Rindi Laura, Peroni Irene, Lari Nicoletta, Bonanni Daniela, Tortoli Enrico, Garzelli Carlo
Abstract excerpt
PPE44 is a member of the Mycobacterium tuberculosis PPE proteins, a polymorphic family of 69 glycine-rich proteins that predictively represent a source of antigenic variation. The genetic diversity of gene ppe44 among clinical isolates has been studied. No genomic polymorphism of ppe44 was found by a PCR-restriction fragment length polymorphism assay using three restriction enzymes. Nucleotide sequencing of gene...
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