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Article

PPE Antigen Rv2430c of Mycobacterium tuberculosis Induces a Strong B-Cell Response

24 Oct 2003

Abstract excerpt

The variation in sequence and length in the C-terminal region among members of the unique PE (Pro-Glu) and PPE (Pro-Pro-Glu) protein families of Mycobacterium tuberculosis is a likely source of antigenic variation, giving rise to the speculation that these protein families could be immunologically important. Based on in silico analysis, we selected a hypothetical open reading frame (ORF) encoding a protein...

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Identifiers

PMID: 14573653
DOI: 10.1128/iai.71.11.6338-6343.2003

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