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Oxygen concentration during mouse oocyte in vitro maturation affects embryo and fetal development

25 Jul 2007

Abstract excerpt

BACKGROUND: Little is known of how the oxygen environment in the ovarian follicle affects oocyte and embryo development, but this has an important impact on the conditions used for in vitro maturation (IVM) of oocytes. We investigated the effect of varying oxygen concentrations during IVM on subsequent pre and post-implantation development. METHODS: IVM of mouse cumulus-oocyte complexes (COCs) was performed under...

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Share to Ovarian function and disorders
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PMID: 17725990
DOI: 10.1093/humrep/dem203

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