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Reduced oxygen concentration improves the developmental competence of mouse oocytes following in vitro maturation

27 Dec 2006

Abstract excerpt

Reduced atmospheric oxygen concentration is beneficial to embryo development; however, optimal oxygen concentration for oocyte maturation remains undetermined. Likewise, there is no consensus of appropriate medium supplementation during maturation. The objective of this study was to determine whether oxygen tension (20% or 5% O2) and epidermal growth factor (EGF) affect oocyte metabolism and subsequent embryo...

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PMID: 17192892
DOI: 10.1002/mrd.20655

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