Article
A type II polyketide synthase is responsible for anthraquinone biosynthesis in Photorhabdus luminescens.
Chembiochem : a European journal of chemical biology - 24 Sept 2007
Brachmann Alexander O, Joyce Susan A, Jenke-Kodama Holger, Schwär Gertrud, Clarke David J, Bode Helge B
Abstract excerpt
Type II polyketide synthases are involved in the biosynthesis of numerous clinically relevant secondary metabolites with potent antibiotic or anticancer activity. Until recently the only known producers of type II PKSs were members of the Gram-positive actimomycetes, well-known producers of secondary metabolites in general. Here we present the second example of a type II PKS from Gram-negative bacteria. We have...
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