Article

Bioinformatic and mechanistic analysis of the palmerolide PKS-NRPS biosynthetic pathway from the microbiome of an Antarctic ascidian

2021-04-06

Abstract excerpt

Complex interactions exist between microbiomes and their hosts. Increasingly, defensive metabolites that have been attributed to host biosynthetic capability are now being recognized as products of host-associated microbes. These unique metabolites often have bioactivity targets in human disease and can be purposed as pharmaceuticals. Polyketides are a complex family of natural products that often serve as defensi...

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Literature Corpus work: 18ae3dbe-7298-573f-abf1-b065e4699242
DOI: 10.1101/2021.04.05.438531

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