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Article

E6/E7 of HPV type 16 promotes cell invasion and metastasis of human breast cancer cells.

Cell cycle (Georgetown, Tex.) - 15 Aug 2007

Yasmeen Amber, Bismar Tarek A, Kandouz Mustapha, Foulkes William D, Desprez Pierre-Yves, Al Moustafa Ala-Eddin

Abstract excerpt

Human papillomaviruses (HPVs) could be important risk factors for breast carcinogenesis and metastasis, as roughly 50% of breast cancers are positive for high-risk HPVs. To determine the role of high-risk HPVs in human breast carcinogenesis and metastasis, we examined the effect of E6/E7 of HPV type 16 in two non-invasive breast cancer cell lines, MCF7 and BT20. We report that E6/E7 of HPV type 16 induces cell...

Read the complete abstract on PubMed

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Share to Cell Transformation, Neoplastic
Share to Mammary Neoplasms, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Neoplasm Invasiveness

Share to Oncogene Proteins, Viral

Share to Papillomavirus E7 Proteins

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Share to Transplantation, Heterologous

Source

Identifiers

PMID: 17721085
DOI: 10.4161/cc.6.16.4555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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