Article
Structural analysis of group II chitinase (ChtII) catalysis completes the puzzle of chitin hydrolysis in insects.
The Journal of biological chemistry - 23 Feb 2018
Chen Wei, Qu Mingbo, Zhou Yong, Yang Qing
Abstract excerpt
Chitin is a linear homopolymer of N-acetyl-β-d-glucosamines and a major structural component of insect cuticles. Chitin hydrolysis involves glycoside hydrolase family 18 (GH18) chitinases. In insects, chitin hydrolysis is essential for periodic shedding of the old cuticle ecdysis and proceeds via a pathway different from that in the well studied bacterial chitinolytic system. Group II chitinase (ChtII) is a...
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