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Article

Quantile-based permutation thresholds for quantitative trait loci hotspots.

Genetics - 1 Aug 2012

Neto Elias Chaibub, Keller Mark P, Broman Andrew F, Attie Alan D, Jansen Ritsert C, Broman Karl W, Yandell Brian S

Abstract excerpt

Quantitative trait loci (QTL) hotspots (genomic locations affecting many traits) are a common feature in genetical genomics studies and are biologically interesting since they may harbor critical regulators. Therefore, statistical procedures to assess the significance of hotspots are of key importance. One approach, randomly allocating observed QTL across the genomic locations separately by trait, implicitly...

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Identifiers

PMID: 22661325
DOI: 10.1534/genetics.112.139451
PMCID: PMC3416013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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