Article
Role of cystic fibrosis transmembrane conductance regulator in patients with chronic sinopulmonary disease.
Chest - 1 Oct 2012
Gonska Tanja, Choi Perry, Stephenson Anne, Ellis Lynda, Martin Sheelagh, Solomon Melinda, Dupuis Annie, Dorfman Ruslan, Zielenski Julian, Ooi Chee Y, Weiser William, Durie Peter R, Tullis Elizabeth
Abstract excerpt
BACKGROUND: Previous studies report a high frequency of mutations in the cystic fibrosis (CF) transmembrane conductance regulator gene (CFTR) in patients with idiopathic bronchiectasis. However, most studies have based their findings on preselected patient groups or have performed limited testing for CF transmembrane conductance regulator (CFTR) dysfunction. The objective of our study was to evaluate the...
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