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Article

The wolframin His611Arg polymorphism influences medication overuse headache.

Neuroscience letters - 13 Sept 2007

Di Lorenzo C, Sances G, Di Lorenzo G, Rengo C, Ghiotto N, Guaschino E, Perrotta A, Santorelli F M, Grieco G S, Troisi A, Siracusano A, Pierelli F, Nappi G, Casali C

Abstract excerpt

Homozygosis for wolframin (WFS1) mutations determines Wolfram syndrome (WS), and common polymorphisms of WFS1 are associated with psychiatric illnesses and dependence behaviour. To test the influence of WFS1 polymorphisms on medication overuse headache (MOH), a chronic headache condition related to symptomatic drugs overuse, we analyzed 82 MOH patients for the WFS1 His611Arg polymorphism, and performed a...

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Identifiers

PMID: 17719176
DOI: 10.1016/j.neulet.2007.07.037

Genes

WFS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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