Article
Combined effect of common gene variants on response to drug withdrawal therapy in medication overuse headache.
European journal of clinical pharmacology - 1 Oct 2014
Cargnin Sarah, Viana Michele, Sances Grazia, Bianchi Marika, Ghiotto Natascia, Tassorelli Cristina, Nappi Giuseppe, Canonico Pier Luigi, Genazzani Armando A, Terrazzino Salvatore
Abstract excerpt
PURPOSE: No information is currently available on genetic determinants of short-term response to drug withdrawal in medication overuse headache (MOH). In the present study, we aimed to evaluate the role of 14 polymorphisms in 8 candidate genes potentially relevant for drug addiction (OPRM1, DRD2, DBH, COMT, BDNF, SLC6A4, 5HT2A, and SLC1A2) as predictors for detoxification outcome of MOH patients at 2 months of...
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