Article
HDAC3 role in medication consumption in medication overuse headache patients: a pilot study.
Human genomics - 5 Nov 2015
Pisanu Claudia, Caproni Stefano, Congiu Donatella, Cupini Letizia M, Squassina Alessio, Patrinos George P, Corbelli Ilenia, Calabresi Paolo, Del Zompo Maria, Sarchielli Paola
Abstract excerpt
BACKGROUND: Medication overuse headache (MOH) is a common and debilitating disorder characterized by generation, perpetuation, and persistence of intense chronic migraine, caused by overuse of analgesics, triptans, or other acute headache compounds. It has been suggested that MOH could share some pathogenetic mechanisms with other kinds of drug addiction. In this regard, histone deacetylases 3 (HDAC3) seems to...
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