Article
Homozygous 825T allele of the GNB3 protein influences the susceptibility of Japanese to dyspepsia.
Digestive diseases and sciences - 1 Mar 2008
Tahara Tomomitsu, Arisawa Tomiyasu, Shibata Tomoyuki, Wang Fangyu, Nakamura Masakatsu, Sakata Mikijyu, Hirata Ichiro, Nakano Hiroshi
Abstract excerpt
The role of genetics in the susceptibility to functional dyspepsia (FD) is not well established. Recently, two different associations were reported between FD and G-protein beta3 (GNB3) subunit gene polymorphism. We aim to clarify the association between GNB3 protein C825T polymorphism and dyspepsia in the Japanese population. Eight-nine dyspeptics and 94 nondyspeptic subjects enrolled in this study. All subjects...
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