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Article

Is there an association between GNbeta3-C825T genotype and lower functional gastrointestinal disorders?

Gastroenterology - 1 Jun 2006

Andresen Viola, Camilleri Michael, Kim H Jae, Stephens Debra A, Carlson Paula J, Talley Nicholas J, Saito Yuri A, Urrutia Raul, Zinsmeister Alan R

Abstract excerpt

BACKGROUND & AIMS: GNbeta3 influences G-protein translation of a majority of ligand-receptor activations. It has been reported that functional dyspepsia (FD) is associated with homozygous genotypes of the C825T polymorphism in the GNbeta3 gene. It is unknown whether the GNbeta3 genotype is associated with lower functional gastrointestinal disorders (FGID). We aimed to compare the prevalence of the different...

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PMID: 16762621
DOI: 10.1053/j.gastro.2006.03.017

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FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Is there an association between GNbeta3-C825T genotype and lower functional gastrointestinal disorders?PMID 16762621Read ↗

Association of genetic variants in GNβ3 with functional dyspepsia: a meta-analysis.Semantic proximity Read ↗

G-Protein Beta3 Subunit C825T Polymorphism in Patients With Overlap Syndrome of Functional Dyspepsia and Irritable Bowel SyndromeSemantic proximity Read ↗

G-protein β3 subunit 825CC genotype is associated with postprandial distress syndrome with impaired gastric emptying and with the feeling of hunger in Japanese.Semantic proximity Read ↗

Functional dyspepsia is associated with GNβ3 C825T and CCK-AR T/C polymorphism.Semantic proximity Read ↗

G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia.Semantic proximity Read ↗

Gastroesophageal reflux disease is associated with the C825T polymorphism in the G-protein beta3 subunit gene (GNB3).Semantic proximity Read ↗

No association of G-protein beta polypeptide 3 polymorphism with irritable bowel syndrome: evidence from a meta-analysis.Semantic proximity Read ↗

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