Article
The G-protein beta3 subunit 825 TT genotype is associated with epigastric pain syndrome-like dyspepsia.
BMC medical genetics - 26 Jan 2010
Oshima Tadayuki, Nakajima Shigemi, Yokoyama Tetsuji, Toyoshima Fumihiko, Sakurai Jun, Tanaka Junji, Tomita Toshihiko, Kim Yongmin, Hori Kazutoshi, Matsumoto Takayuki, Miwa Hiroto
Abstract excerpt
BACKGROUND: Although familial clustering of functional dyspepsia (FD) has been reported, the role of genetics in the susceptibility to FD is still not well understood. Several reports indicate an association between FD and G-protein beta3 (GNB3) subunit gene polymorphism (C825T); however, these studies had small sample sizes and the findings are inconclusive. In the present study we clarified the association...
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