Article
Class I histone deacetylase Thd1p promotes global chromatin condensation in Tetrahymena thermophila.
Eukaryotic cell - 1 Oct 2007
Parker Kathryn, Maxson Julia, Mooney Alissa, Wiley Emily A
Abstract excerpt
Class I histone deacetylases (HDACs) regulate DNA-templated processes such as transcription. They act both at specific loci and more generally across global chromatin, contributing to acetylation patterns that may underlie large-scale chromatin dynamics. Although hypoacetylation is correlated with highly condensed chromatin, little is known about the contribution of individual HDACs to chromatin condensation...
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