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Article

Benefits of a Recombination-Proficient Escherichia coli System for Adaptive Laboratory Evolution.

Applied and environmental microbiology - 15 Nov 2016

Peabody George, Winkler James, Fountain Weston, Castro David A, Leiva-Aravena Enzo, Kao Katy C

Abstract excerpt

Adaptive laboratory evolution typically involves the propagation of organisms asexually to select for mutants with the desired phenotypes. However, asexual evolution is prone to competition among beneficial mutations (clonal interference) and the accumulation of hitchhiking and neutral mutations. The benefits of horizontal gene transfer toward overcoming these known disadvantages of asexual evolution were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27613685
DOI: 10.1128/AEM.01850-16
PMCID: PMC5086567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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