Article
Effect of CYP1A1 MspI polymorphism on cigarette smoking related coronary artery disease and diabetes.
Atherosclerosis - 1 Jun 2002
Wang Xing Li, Greco Marissa, Sim Ah Siew, Duarte Natalia, Wang Jian, Wilcken David E L
Abstract excerpt
CYP1A1, is one of the key detoxifying enzymes catabolizing cigarette smoking derived toxins and may be relevant to smoking-induced atherogenesis. Recently a CYP1A1 MspI polymorphism at the 3'-flanking region of the gene has been found to be associated with smoking related cancer risk and may, therefore, also be associated with vascular disease. To explore this, we investigated interactive effects between smoking...
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