Article
[Genetic polymorphism of cytochrome P4501A1 and susceptibility to laryngeal carcinoma].
Zhonghua er bi yan hou ke za zhi - 1 Oct 2002
Lei Dapeng, Pan Xinliang, Guo Chenhong, Luan Xinyong, Xu Fenglei, Zhang Liqiang, Liu Dayu
Abstract excerpt
OBJECTIVE: To assess the possible relation between the MspI polymorphism of Cytochrome P4501A1(CYP1A1) gene and the susceptibility to laryngeal cancer. METHODS: The genotypes of CYP1A1 MspI site were detected using the methods of polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) in 62 cases of laryngeal squamous carcinoma and 56 healthy controls. Genetic risk of CYP1A1 genotypes was...
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