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Article

Human immune polymorphisms associated with the risk of cryptococcal disease.

Immunology - 1 Feb 2022

Onyishi Chinaemerem U, May Robin C

Abstract excerpt

Cryptococcus neoformans is an opportunistic fungal pathogen that can cause lethal cryptococcal meningitis in immunocompromised individuals such as those with HIV/AIDS. In addition, cryptococcal infections occasionally arise in immunocompetent individuals or those with previously undiagnosed immunodeficiencies. The course of cryptococcosis is highly variable in both patient groups, and there is rapidly growing...

Topics

Adaptive Immunity
Animals
Biomarkers
Cryptococcosis
Cryptococcus neoformans
Disease Susceptibility
Gene Expression Regulation
Genetic Predisposition to Disease
Genetic Variation
Host-Pathogen Interactions
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunity, Innate

Immunocompromised Host

Immunogenetic Phenomena

Polymorphism, Genetic

Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 34716931
DOI: 10.1111/imm.13425
PMCID: PMC9426616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34716931-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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