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The zebrafish erythropoietin: Functional identification and biochemical characterization

10 Aug 2007

Abstract excerpt

In the present study, the zebrafish epo cDNA was cloned. The encoded protein displays 90%, 55% and 32% identity to the Epo from carp, fugu and human, respectively. Through RT-PCR, the expression of zepo mRNA was mainly in the heart and liver. In the COS-1 cell transfection experiments, the recombinant zEpo-HA protein was efficiently secreted into the culture medium as a glycoprotein and the carbohydrate moiety...

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PMID: 17706649
DOI: 10.1016/j.febslet.2007.07.073

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