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Erythropoietin gene from a teleost fish, Fugu rubripes

18 May 2004

Abstract excerpt

In this paper we report the cloning and characterization of the erythropoietin (Epo) gene from the pufferfish, Fugu rubripes. This is the first nonmammalian Epo gene to be cloned. The Fugu Epo comprises 5 exons and 4 introns similar to the human EPO, and encodes a 185-amino acid protein that is 32% to 34% identical to Epo from various mammals. The synteny of genes at the Epo locus is conserved between the Fugu...

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PMID: 15142879
DOI: 10.1182/blood-2003-10-3404

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