Article
Inheritance of nevus number and size in melanoma and dysplastic nevus syndrome kindreds.
Journal of the National Cancer Institute - 4 Dec 1991
Goldgar D E, Cannon-Albright L A, Meyer L J, Piepkorn M W, Zone J J, Skolnick M H
Abstract excerpt
Previous studies of the genetics of melanoma have focused on the dysplastic nevus syndrome (DNS). The variability in clinical and histopathological expression of affected individuals, however, has made definition and diagnosis of the syndrome difficult and subjective. Independent of the DNS, case-control studies have demonstrated the total number of nevi to be a significant risk factor for melanoma. In this...
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