Article
Structure of membrane-embedded M13 major coat protein is insensitive to hydrophobic stress.
Biophysical journal - 15 Nov 2007
Vos Werner L, Schor Marieke, Nazarov Petr V, Koehorst Rob B M, Spruijt Ruud B, Hemminga Marcus A
Abstract excerpt
The structure of a membrane-embedded alpha-helical reference protein, the M13 major coat protein, is characterized under different conditions of hydrophobic mismatch using fluorescence resonance energy transfer in combination with high-throughput mutagenesis. We show that the structure is similar in both thin (14:1) and thick (20:1) phospholipid bilayers, indicating that the protein does not undergo large...
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