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Article

CYP2D6*4 polymorphism is associated with statin-induced muscle effects.

Pharmacogenetics and genomics - 1 Sept 2007

Frudakis Tony N, Thomas Matthew J, Ginjupalli Siva N, Handelin Barbara, Gabriel Richard, Gomez Hector J

Abstract excerpt

Statin use is associated with a variety of overtly related muscle symptoms including muscle pain, myalgia, creatine kinase elevations without pain with myolysis and myositis (rhabdomyolysis), a potentially fatal side effect that led to the withdrawal of cerivastatin in 2001. Unintended drug respo...

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Source

Identifiers

PMID: 17700359
DOI: 10.1097/FPC.0b013e328012d0a9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17700359-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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