Article
GLH-1, the C. elegans P granule protein, is controlled by the JNK KGB-1 and by the COP9 subunit CSN-5.
Development (Cambridge, England) - 1 Sept 2007
Orsborn April M, Li Wensheng, McEwen Tamara J, Mizuno Tomoaki, Kuzmin Evgeny, Matsumoto Kunihiro, Bennett Karen L
Abstract excerpt
The GLHs (germline RNA helicases) are constitutive components of the germline-specific P granules in the nematode Caenorhabditis elegans and are essential for fertility, yet how GLH proteins are regulated remains unknown. KGB-1 and CSN-5 are both GLH binding partners, previously identified by two-hybrid interactions. KGB-1 is a MAP kinase in the Jun N-terminal kinase (JNK) subfamily, whereas CSN-5 is a subunit of...
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