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Article

Memory CD8+ T cells mediate antibacterial immunity via CCL3 activation of TNF/ROI+ phagocytes.

The Journal of experimental medicine - 3 Sept 2007

Narni-Mancinelli Emilie, Campisi Laura, Bassand Delphine, Cazareth Julie, Gounon Pierre, Glaichenhaus Nicolas, Lauvau Grégoire

Abstract excerpt

Cytolysis, interferon gamma and tumor necrosis factor (TNF) alpha secretion are major effector mechanisms of memory CD8+ T cells that are believed to be required for immunological protection in vivo. By using mutants of the intracellular bacterium Listeria monocytogenes, we found that none of these effector activities is sufficient to protect against secondary infection with wild-type (WT) bacteria. We...

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Source

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Identifiers

PMID: 17698589
DOI: 10.1084/jem.20070204
PMCID: PMC2118695

Genes

CCL3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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