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Bacterial inhibition of CD8 <sup>+</sup> T-cells mediated cell death promotes neuroinvasion and within-host persistence

2020-11-20

Abstract excerpt

Central nervous system infections are amongst the most severe 1,2 , yet the mechanisms by which pathogens access the brain remain poorly understood. The model microorganism Listeria monocytogenes (Lm) is a major foodborne pathogen that causes neurolisteriosis, one of the deadliest central nervous system infections 3,4 . While immunosuppression is a well-established host risk factor for neurolisteriosis 3,5 , l...

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Literature Corpus work
5e773d97-59b2-59d8-b704-f492e7958e19
DOI
10.1101/2020.11.20.384974
Open publication

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Bacterial inhibition of CD8 <sup>+</sup> T-cells mediated cell death promotes neuroinvasion and within-host persistenceDOI 10.1101/2020.11.20.384974
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