Article
The rate of pyrin mutations in critically ill patients with systemic inflammatory response syndrome and sepsis: a pilot study.
The Journal of rheumatology - 1 Oct 2007
Koc Bayram, Oktenli Cagatay, Bulucu Fatih, Karadurmus Nuri, Sanisoglu S Yavuz, Gul Davut
Abstract excerpt
OBJECTIVE: The role of individual genetic differences in susceptibility to systemic inflammatory response syndrome (SIRS) and sepsis is generally unrecognized or underestimated. We investigated the rate of pyrin mutations in critically ill patients with SIRS and sepsis, and compared whether carriers for pyrin mutations are associated with respect to the frequency of and certain features of sepsis and SIRS....
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