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Article

Protective Role of Cytochrome P450 Oxidoreductase in Sepsis Development: Genetic and Phenotypic Analyses.

The Tohoku journal of experimental medicine - 12 Mar 2026

Li Yueying, Zeng Zhiwen, Lin Weixiong

Abstract excerpt

Currently, the pathogenesis of sepsis has not been fully elucidated. This study aimed to explore the role of cytochrome P450 oxidoreductase (POR) in this disease. Specifically, two-sample Mendelian randomization, multivariate Mendelian randomization, and summary data-based Mendelian randomization methods were employed to assess the genetic impact of peripheral POR protein and POR genes from multiple tissue...

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Identifiers

PMID: 41192874
DOI: 10.1620/tjem.2025.J133

Genes

POR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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