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Advancements in the Understanding of Paclitaxel Metabolism in Tissue Culture

29 Jul 2007

Abstract excerpt

Paclitaxel is a potent chemotherapeutic agent approved in the treatment of a variety of cancers, and under evaluation for the treatment of Alzheimer's and heart disease. Originally isolated from Taxus brevifolia, this highly substituted ring diterpenoid belongs to a family of plant secondary metabolites known as taxoids. Paclitaxel is currently supplied through both a semi-synthetic process and plant cell...

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PMID: 17691991
DOI: 10.2174/138920107781387393

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