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Regulatory microRNAs and phasiRNAs of paclitaxel biosynthesis in Taxus chinensis

8 May 2024

Abstract excerpt

Paclitaxel (trade name Taxol) is a rare diterpenoid with anticancer activity isolated from Taxus. At present, paclitaxel is mainly produced by the semi-synthetic method using extract of Taxus tissues as raw materials. The studies of regulatory mechanisms in paclitaxel biosynthesis would promote the production of paclitaxel through tissue/cell culture approaches. Here, we systematically identified 990...

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PMID: 38779066
DOI: 10.3389/fpls.2024.1403060

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