Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in <i>Taxus</i> suspension cultures

18 Nov 2011

Abstract excerpt

Variability in product accumulation is one of the major obstacles limiting the widespread commercialization of plant cell culture technology to supply natural product pharmaceuticals. Despite extensive process engineering efforts, which have led to increased yields, plant cells exhibit variability in productivity that is poorly understood. Elicitation of Taxus cultures with methyl jasmonate (MeJA) induces...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Treatment and Pharmacology
Share to Plant Pathogens and Fungal Diseases
Share to Plant tissue culture and regeneration

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22095859
DOI: 10.1002/biot.201100183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in <i>Taxus</i> suspension culturesPMID 22095859Read ↗

Effect of subculture and elicitation on instability of taxol production in Taxus sp. suspension cultures.Semantic proximity Read ↗

Advancements in the Understanding of Paclitaxel Metabolism in Tissue CultureSemantic proximity Read ↗

Flow cytometric methods to investigate culture heterogeneities for plant metabolic engineering.Semantic proximity Read ↗

Genetic approaches in improving biotechnological production of taxanes: An updateSemantic proximity Read ↗

Synergistic effect of cyclodextrins and methyl jasmonate on taxane production in <i>Taxus x media</i> cell culturesSemantic proximity Read ↗

Changes in gene transcription and taxane production in elicited cell cultures of Taxus×media and Taxus globosaSemantic proximity Read ↗

Insights into the control of taxane metabolism: Molecular, cellular, and metabolic changes induced by elicitation in Taxus baccata cell suspensionsSemantic proximity Read ↗

Transcriptional profile of Taxus chinensis cells in response to methyl jasmonateSemantic proximity Read ↗

Assessment of genetic and epigenetic variation during long-term Taxus cell culture.Semantic proximity Read ↗

A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp.Semantic proximity Read ↗

Taxol production in plant cell culture comes of ageSemantic proximity Read ↗

Recent Advances in Metabolic Engineering, Protein Engineering, and Transcriptome-Guided Insights Toward Synthetic Production of TaxolSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.