Article

Getting to the bottom of Taxol biosynthesis by fungi

2013-04-08

Abstract excerpt

Taxol (paclitaxel) is a highly-oxygenated diterpenoid natural product first isolated from the pacific yew tree ( Taxus brevifolia ). It is one of the most widely used anticancer drugs. Soon after the discovery of its unique mode of action and the resulting high demand, an extensive search was initiated for alternative sources to replace the slow-growing and scarce pacific yew. Thus far, however, Taxol and related...

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Literature Corpus work: 2402ea56-18b9-5b76-9955-80dce09b42a3
DOI: 10.1007/s13225-013-0228-7

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