Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recent Advances in Metabolic Engineering, Protein Engineering, and Transcriptome-Guided Insights Toward Synthetic Production of Taxol

5 Feb 2021

Abstract excerpt

The diterpenoid paclitaxel (Taxol ® ) is a blockbuster anticancer agent that was originally isolated from the Pacific yew ( Taxus brevifolia ) five decades ago. Despite the wealth of information gained over the years on Taxol research, there still remains supply issues to meet increasing clinical demand. Although alternative Taxol production methods have been developed, they still face several drawbacks that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Treatment and Pharmacology
Share to Microbial Natural Products and Biosynthesis
Share to Plant biochemistry and biosynthesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33614616
DOI: 10.3389/fbioe.2021.632269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recent Advances in Metabolic Engineering, Protein Engineering, and Transcriptome-Guided Insights Toward Synthetic Production of TaxolPMID 33614616Read ↗

Advancements in the Understanding of Paclitaxel Metabolism in Tissue CultureSemantic proximity Read ↗

Getting to the bottom of Taxol biosynthesis by fungiSemantic proximity Read ↗

Regulatory microRNAs and phasiRNAs of paclitaxel biosynthesis in Taxus chinensisSemantic proximity Read ↗

Genetic approaches in improving biotechnological production of taxanes: An updateSemantic proximity Read ↗

A novel step towards the heterologous biosynthesis of paclitaxel: Characterization of T1βOH taxane hydroxylaseSemantic proximity Read ↗

A review: recent advances and future prospects of taxol-producing endophytic fungi.Semantic proximity Read ↗

Gene Discovery of Modular Diterpene Metabolism in Nonmodel SystemsSemantic proximity Read ↗

From Taxus to paclitaxel: Opportunities and challenges for urban agriculture to promote human healthSemantic proximity Read ↗

Omic analysis of the endangered Taxaceae species Pseudotaxus chienii revealed the differences in taxol biosynthesis pathway between Pseudotaxus and Taxus yunnanensis trees.Semantic proximity Read ↗

A rational approach to improving the biotechnological production of taxanes in plant cell cultures of Taxus spp.Semantic proximity Read ↗

Screening of taxol biosynthesis-related genes in taxol produced from Nodulisporium sylviforme HDF-68 by mRNA differential displaySemantic proximity Read ↗

Contribution of taxane biosynthetic pathway gene expression to observed variability in paclitaxel accumulation in <i>Taxus</i> suspension culturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.