Article
[Association of single nucleotide polymorphisms of IL-1b with lumbar disc disease].
Yi chuan = Hereditas - 1 Aug 2007
Ye Wei, Ma Ruo-Fan, Su Pei-Qiang, Huang Dong-Sheng, Liu Shang-Li, Chen Wei-Jian, Wang Xin-Guang
Abstract excerpt
This study was to explore the relationships between (-511)T>C and (+3954)C>T single nucleotide polymorphisms(SNP) in IL-1beta gene with lumbar intervertebral disc disease. We analyzed (-511)T>C and (+3954)C>T SNP in IL-1beta gene by the polymerase chain reaction-restriction fragment length polymorphism and electrophoresis methods respectively in 81 cases with lumbar disc disease and 101 healthy controls. The...
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