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Article

Meta-analysis of the effects of genetic polymorphisms on intervertebral disc degeneration.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Aug 2017

Rigal J, Léglise A, Barnetche T, Cogniet A, Aunoble S, Le Huec J C

Abstract excerpt

INTRODUCTION: Chronic low back pain is a significant public health issue. Both its direct and indirect cost represents tens of billions of US dollars. Although chronic low back pain can be the result of many factors, the predominant cause is disc degeneration. Recent studies have shown genetic involvement in up to 74% of cases. This study aimed to evaluate genetic risk factors of disc degeneration by performing a...

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Identifiers

PMID: 28551829
DOI: 10.1007/s00586-017-5146-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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